Head, Microchemistry and Proteomics Core facility, Sloan Kettering Institute
Memorial Sloan Kettering Cancer Center
Location: New York, New York
Academic / Research
Internal Number: 59340
At Memorial Sloan Kettering (MSK), we're not only changing the way we treat cancer, but also the way the world thinks about it. By working together and pushing forward with innovation and discovery, we're driving excellence and improving outcomes. We're treating cancer, one patient at a time. Join us and make a difference every day.
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The Sloan Kettering Institute at the Memorial Sloan Kettering Cancer Center (MSK) is seeking innovative individuals with a strong record of accomplishments in proteomics to lead its Microchemistry & Proteomics core facility. SKI offers a highly interactive basic and translational science research environment (www.ski.edu) and is in a multi-institutional academic community. This is a laboratory-track faculty position fully supported by the institution.
The Microchemistry & Proteomics Core supports research programs at MSK by performing mass spectrometry based sequence analyses of proteins and peptides for the purpose of identification, quantitation, chemical and post-translational modification (PTM). The Core Head is responsible for setting the short, medium- and long-term scientific directions of the core. They oversee hiring, training, mentoring of trainees, and staff career development. The core head operational' s responsibilities encompass oversight of advanced methods development and implementation, technical troubleshooting, instruments maintenance, scientific consultation and, liaising with the scientific community to grow a sustainable state-of-the-art operation.
The Core Head is also expected to develop innovative methodologies such as single-cell proteomics, comprehensive and genome-scale proteogenomics, chemical proteomics, spatial and imaging proteomics, immunoproteomics, multiplexed high-throughput proteomics, and intact macromolecular and complex proteomics.
Applicants should have a PhD degree and five to ten years of relevant post-degree experience necessary to develop a technologically innovative environment. Expertise with quantitative high-resolution mass spectrometry proteomics is required, including current state-of-the-art preanalytical and analytical methods (isobaric and metabolic isotope labeling, multidimensional separations, nanoscale liquid chromatography, nanoelectrospray and laser desorption ionization, high-resolution Orbitrap and time-of-flight mass spectrometry). Direct experience with Thermo, Bruker, AB Sciex or Waters chromatographs/mass spectrometers is required. Expertise in computational analysis of data-dependent, targeted, and data-independent proteomics data (using PEAKS, Byonic, MSFragger, ProteomeDiscoverer, Skyline, or Spectronaut software) is also required. Prior experience in managing a proteomics core facility in a multiuser environment is highly preferred. Strong communication and interpersonal skills are required.
Inquiries may be sent to Dr. Agnes Viale, Director of Core facilities operations at firstname.lastname@example.org.
The deadline for applications is January 15th.
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At Memorial Sloan Kettering (MSK), we’re not only changing the way we treat cancer, but also the way the world thinks about it. By working together and pushing forward with innovation and discovery, we’re driving excellence and improving outcomes. For the 28th year, MSK has been named a top hospital for cancer by U.S. News & World Report. We are proud to be on Becker’s Healthcare list as one of the 150 Great Places to Work in Healthcare in 2018, as well as one of Glassdoor’s Employees’ Choice Best Place to Work for 2018. We’re treating cancer, one patient at a time. Join us and make a difference every day.